Found 60 matching trials
Neoadjuvant Therapy With Conservative Surgery vs. Up-front Conservative Surgery for BRAF V600E-Mutated Ameloblastoma
PHASE2Ameloblastoma is the most common benign odontogenic tumor, characterized by...
Location
Multiple Locations
TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma
PHASE2This phase 2 trial will investigate the efficacy and safety of trametinib a...
Location
Universitair Ziekenhuis Brussel
Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease
PHASE2Erdheim-Chester Diseases (ECD) is a very rare non-Langerhans cell histiocyt...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
Melanoma Metastasized to the Brain and Steroids
PHASE2This clinical trial is to clarify whether treatment with a checkpoint inhib...
Location
Herlev Universityhospital
Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites
PHASE2This is a global, multi-centre, open-label, study of GSK2118436 conducted i...
Location
GSK Investigational Site
PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer
PHASE2The purpose of this study is to find out whether a drug called PDR001, comb...
Status
Active Not Recruiting
Location
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Dabrafenib and Trametinib Combination as a Neoadjuvant Strategy in BRAF-positive Anaplastic Thyroid Cancer
PHASE2The aim of the study was to evaluate the effectiveness of combination thera...
Location
Saint-Petersburg State University (SPSU) N.I.Pirogov Clinic of High Medical Technologies
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
PHASE2This phase II trial studies how well de-escalating the drugs dabrafenib and...
Location
University of Alabama at Birmingham
Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With Melanoma
PHASE1Present clinical study will be conducted in China to evaluate the pharmacok...
Location
Multiple Locations
A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma
PHASE3The purpose of this study was to evaluate safety and efficacy of the combin...
Location
California Cancer Associates for Research and Excellence